The Titans shocked NFL fans last week when they recorded a tremendous comeback win over the Kansas City Chiefs in the AFC Wild Card round.
And they will be looking to upset the odds once again when they face Tom Brady and Co.
The Patriots secured the No 1 seed in the AFC thanks to their 13-3 record in the regular season.
And they haven’t lost a Divisional Round game in seven years since losing to the New York Jets in 2011.
Experience could be the key here for both teams with Brady having played 34 playoff games while Marcus Mariota has featured in just one.
It promises to be an interested match-up and here is how you can follow the game live.
How to watch New England Patriots vs Tennessee Titans on TV
The game is available to watch live on Sky Sports with coverage starting at 1am today with the match scheduled to begin at 1:15am.
Sky Sports Main Event, available on Sky channel 401, is the home of NFL, while Virgin Media customers can watch the action on channel 511.
How can I stream New England Patriots vs Tennessee Titans live online?
If you’re unable to get in front of a TV, Sky Sports customers are able to watch the game live via Sky Go.
American viewers can head to CBS All Access for a live stream of the game.